Comprehensive preclinical characterization of IPB29, a pan-coronavirus fusion inhibitor under clinical trials.
Publication date: May 01, 2025IPB29 is a lipopeptide-based coronavirus fusion inhibitor with the potent, broad-spectrum ...
Clinical Trials
Information on Covid-19 clinical trials
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Long-term safety, tolerability, and efficacy of eptinezumab in chronic cluster headache (CHRONICLE): an open-label safety trial.
Publication date: May 01, 2025Chronic cluster headache is an uncommon but highly debilitating primary headache ... -
FirstCPR: A pragmatic community organisation-based cluster randomised trial to increase community training and preparedness to respond to out-of-hospital cardiac arrest.
Publication date: May 01, 2025Bystander cardiopulmonary resuscitation (CPR) and defibrillation improve out-of-hospital cardiac arrest survival. ... -
Effect of a web-based intervention on the mental health of informal caregivers of the elderly: a randomized controlled trial.
Publication date: Apr 18, 2025Iran’s demographic trends indicate significant aging, with intensive caregiving linked to ... -
Effectiveness of telerehabilitation-supported exercises in patients with temporomandibular disorders with probable sleep bruxism during the COVID-19 pandemic: A randomized controlled trial.
Publication date: Apr 18, 2025This study evaluated telerehabilitation-supported exercises’ effects on pain, neck disability, anxiety, ... -
Cost-effectiveness of a group psychological intervention for postnatal depression in British south Asian women: an economic evaluation from the ROSHNI-2 trial.
Publication date: May 01, 2025Minority ethnic groups often face ethnocultural barriers in accessing mental health ... -
Creative strengthening groups as a potential intervention to enhance job satisfaction and reduce levels of burnout in healthcare professionals: results from the randomized controlled trial UPGRADE.
Publication date: Apr 17, 2025Healthcare professionals often face substantial work-related burdens. A large body of ... -
Attitudes Toward COVID-19 Vaccination and Clinical Trials Among Saudi University Students.
Publication date: Apr 16, 2025The implementation of a global COVID-19 vaccination campaign has been one ... -
Digital, Personalized Clinical Trials Among Older Adults, Lessons Learned From the COVID-19 Pandemic, and Directions for the Future: Aggregated Feasibility Data From Three Trials Among Older Adults.
Publication date: Apr 16, 2025The COVID-19 pandemic was extremely disruptive to clinical practice and research. ... -
Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial.
Publication date: Apr 16, 2025Negative attitudes toward vaccines and suboptimal vaccination rates among African American ... -
Effects of behavioral intervention components to increase COVID-19 testing for African American/Black and Latine frontline essential workers not up-to-date on COVID-19 vaccination: Results of an optimization randomized controlled trial.
Publication date: Apr 17, 2025Racial/ethnic disparities in COVID-19, including incidence, hospitalization, and death rates, are ... -
STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symptoms after COVID-19 infection.
Publication date: Apr 14, 2025Increasing awareness of the high frequency, wide spectrum and disabling nature ... -
MultifocAL COntact Lenses for Myopia (MALCOLM) control in Australian children: a study protocol for a double-blind, contralateral eye, non-inferiority, randomised controlled clinical trial.
Publication date: Apr 14, 2025Myopia is the most common refractive error worldwide, but each dioptre ... -
Ten sessions of hyperbaric oxygen versus sham treatment in patients with long covid (HOT-LoCO): a randomised, placebo-controlled, double-blind, phase II trial.
Publication date: Apr 14, 2025To evaluate if 10 sessions of hyperbaric oxygen treatments (HBOTs) improve ... -
Replacing Mycophenolate Mofetil by Everolimus in Kidney Transplant Recipients to Increase Vaccine Immunogenicity: Results of a Randomized Controlled Trial.
Publication date: Apr 15, 2025Vaccine immunogenicity is reduced in kidney transplant recipients (KTRs), especially in ... -
Bolstering agreement with scarce resource allocation policy using education: a post hoc analysis of a randomized controlled trial.
Publication date: Apr 14, 2025The COVID- 19 pandemic prompted rapid development of scarce resource allocation ... -
Efficacy of tocilizumab for hospitalized patients with COVID-19 pneumonia and high IL-6 levels: A randomized controlled trial.
Publication date: Apr 15, 2025The objective of this clinical trial is to evaluate the efficacy ... -
iCogCA to Promote Cognitive Health Through Digital Group Interventions for Individuals Living With a Schizophrenia Spectrum Disorder: Protocol for a Nonrandomized Concurrent Controlled Trial.
Publication date: Apr 15, 2025Cognitive impairments are a key aspect of schizophrenia spectrum disorders (SSDs), ... -
Effectiveness of Physiotherapy for Improving Participation, Gross Motor Function, Gait and Balance in Children and Adolescents with Cerebral Palsy: Study Protocol for a Randomized Controlled Trial.
Publication date: Mar 24, 2025Background: People with cerebral palsy (CP) present with limitations in gait ... -
The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-Blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID.
Publication date: May 01, 2025Individuals with long COVID lack evidence-based treatments and have difficulty participating ... -
Does enhanced educational intervention reduce breakthrough infection and mental health problems via improving acceptance of COVID-19 booster shots in Chinese non-healthcare workers: A randomized controlled trial?
Publication date: May 01, 2025Despite vaccination and booster shots proving more effective than workplace measures ...